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KISSPEPTIN-10
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KISSPEPTIN-10

$60.00

GPR54/KISS1R receptor agonist — synthetic decapeptide, minimal active kisspeptin fragment Central gatekeeper of the hypothalamic-pituitary-gonadal axis in published preclinical research Research-grade · CAS 374675-21-5 For in vitro reproductive neuroendocrine research only

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Kisspeptin-10 10mg — GPR54 Agonist

The discovery that kisspeptin-GPR54 signaling controls the onset of puberty and governs reproductive neuroendocrine function is considered one of the most important findings in reproductive biology of the past twenty years. Kisspeptin-10 (Metastin 45-54) is the minimal active fragment — ten amino acids that retain full agonist activity at the GPR54 receptor (KISS1R), making it the standard reference compound in this field.

Specifications

 

Amino Acids 10
Receptor Target GPR54 / KISS1R
CAS Number 374675-21-5
Form Lyophilized powder
Quantity 10mg per vial

The HPG axis gatekeeper

Kisspeptin-10 activates GPR54 receptors on GnRH neurons, triggering gonadotropin-releasing hormone secretion and downstream LH and FSH release. This makes the kisspeptin-GPR54 system the critical upstream gate in the hypothalamic-pituitary-gonadal axis. Receptor binding studies confirm that the decapeptide retains the full agonist potency of longer isoforms (Kp-54, Kp-14, Kp-13) — the C-terminal ten residues are where the action is.

Research applications

  • GPR54/KISS1R receptor binding and activation
  • GnRH neuron signaling and HPG axis studies
  • LH and FSH secretion kinetics
  • Comparative kisspeptin isoform structure-activity research
  • Reproductive neuroendocrine pathway studies

Quality and testing

Every Heritage Labs compound is manufactured to research-grade standards and shipped in protective packaging.

Storage

  • Lyophilized: -20°C
  • Reconstituted: 2-8°C, use within 30 days

For laboratory research use only. Not for human or veterinary use.

For laboratory research use only. Not for human or veterinary use. This product is not a drug or supplement and is not intended to diagnose, treat, cure, or prevent any disease.

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